VINCA ALKALOID TOXICITY

Course overview

VINCA ALKALOIDS, WHICH BELONG TO A CLASS OF CELL CYCLE PHASE M SPECIFIC ANTI-TUBULIN AGENTS ARE ONE OF THE FIRST PLANT ALKALOIDS TO BE DEVELOPED FOR USE AS ANTI-CANCER AGENTS IN HUMANS. THIS ACTIVITY DESCRIBES THE INCIDENCE, ETIOLOGY, CLINICAL FEATURES, EXAMINATION FINDINGS, DIFFERENTIAL DIAGNOSIS, ASSESSMENT, AND MANAGEMENT OF SYSTEMIC EFFECTS OF VINCA ALKALOIDS, WITH AN EMPHASIS ON VINCRISTINE-INDUCED NEUROTOXICITY.