DEXTROMETHORPHAN

Course overview

DEXTROMETHORPHAN RECEIVED FDA APPROVAL IN 1958 FOR ITS USE AS A COUGH SUPPRESSANT. IT IS ONE OF THE MOST COMMON COMPOUNDS FOUND IN MOST OVER-THE-COUNTER ANTITUSSIVES FOR THE PAST 50 YEARS. IN 2010, THE FDA APPROVED THE USE OF DEXTROMETHORPHAN FOR PSEUDOBULBAR AFFECT IN COMBINATION WITH QUINIDINE. THIS ACTIVITY WILL HIGHLIGHT THE MECHANISM OF ACTION, ADVERSE EVENT PROFILE, APPROVED AND OFF-LABEL USES, DOSING, PHARMACODYNAMICS, PHARMACOKINETICS, MONITORING, RELEVANT INTERACTIONS OF DEXTROMETHORPHAN, PERTINENT FOR MEMBERS OF THE INTERPROFESSIONAL TEAM USING DEXTROMETHORPHAN FOR ANY OF ITS INTENDED INDICATIONS.