HYPOKALEMIC PERIODIC PARALYSIS

Course overview

HYPOKALEMIC PERIODIC PARALYSIS IS A RARE CHANNELOPATHY CAUSED BY THE SKELETAL MUSCLE ION CHANNEL MUTATIONS, COMMONLY CALCIUM CHANNEL AND LESS COMMONLY SODIUM CHANNELS. THE PATIENTS CHARACTERISTICALLY PRESENT WITH SUDDEN ONSET OF GENERALIZED OR FOCAL FLACCID PARALYSIS ASSOCIATED WITH HYPOKALEMIA, WHICH PERSISTS FOR SEVERAL HOURS BEFORE IT RESOLVES SPONTANEOUSLY. TO AVOID THE MORBIDITY ASSOCIATED WITH THE CONDITION, IT SHOULD BE DIAGNOSED AND TREATED WITH PROPHYLACTIC THERAPY. THIS ACTIVITY REVIEWS THE EVALUATION AND TREATMENT OF HYPOKALEMIC PERIODIC PARALYSIS AND HIGHLIGHTS THE ROLE OF THE INTERPROFESSIONAL TEAM IN EVALUATING AND TREATING THIS CONDITION.