CHRONIC MYELOGENOUS LEUKEMIA

Course overview

CHRONIC MYELOID LEUKEMIA (CML), BCR-ABL1-POSITIVE, IS CLASSIFIED AS A MYELOPROLIFERATIVE NEOPLASM PREDOMINANTLY COMPOSED OF PROLIFERATING GRANULOCYTES AND DETERMINED TO HAVE THE PHILADELPHIA CHROMOSOME/TRANSLOCATION T(9;22)(Q34;Q11.2). CML AFFECTS BOTH THE PERIPHERAL BLOOD AND THE BONE MARROW. THERE IS AN INCREASED INCIDENCE OF CML AMONG ATOMIC BOMB SURVIVORS; HOWEVER, THE PREDISPOSING RISK FACTORS ARE UNKNOWN. THIS ACTIVITY REVIEWS THE PATHOPHYSIOLOGY, EVALUATION, AND MANAGEMENT OF CHRONIC MYELOID LEUKEMIA (CML) AND EXPLAINS THE ROLE OF THE INTERPROFESSIONAL TEAM IN CARING FOR PATIENTS WITH THIS CONDITION.