MULTIPLE ENDOCRINE NEOPLASIAS TYPE 4

Course overview

MULTIPLE ENDOCRINE NEOPLASIA (MEN) CONSTITUTES A GROUP OF AUTOSOMAL DOMINANT DISORDERS CHARACTERIZED BY A BROAD SPECTRUM OF ENDOCRINE AND NONENDOCRINE DISEASES. MEN IS DIVIDED INTO DIFFERENT TYPES DEPENDING ON THE CLINICAL PRESENTATIONS AND GENETIC MUTATION. MEN TYPE 1 (MEN1) IS THE MOST COMMON MEN SYNDROME. MEN TYPE 4 (MEN4) IS A RARE AUTOSOMAL DOMINANT ENDOCRINE TUMOR SYNDROME. THE MOST COMMON TUMORS SEEN IN THIS CONDITION INVOLVE THE PARATHYROID GLANDS, ANTERIOR PITUITARY, AND GASTRO-ENTERO-PANCREATIC NEUROENDOCRINE TISSUES. THIS ACTIVITY REVIEWS THE EVALUATION AND MANAGEMENT OF MEN4 AND HIGHLIGHTS THE ROLE OF THE INTERPROFESSIONAL TEAM IN IMPROVING OUTCOMES FOR PATIENTS WITH THIS CONDITION.