BEMPEDOIC ACID

Course overview

BEMPEDOIC ACID IS A LIPID-LOWERING AGENT USED TO REDUCE THE LOW-DENSITY LIPOPROTEIN CHOLESTEROL (LDL-C) LEVELS IN THE BLOOD. THE U.S. FOOD AND DRUG ADMINISTRATION (FDA) HAS APPROVED THIS DRUG AS AN ADJUVANT TO MAXIMALLY TOLERATED STATIN THERAPY TO LOWER LDL-C LEVELS, SPECIFICALLY FOR PATIENTS WITH ATHEROSCLEROTIC CARDIOVASCULAR DISEASE (ASCVD) AND HETEROZYGOUS FAMILIAL HYPERCHOLESTEROLEMIA (HEFH). IN ADDITION, BEMPEDOIC ACID CAN ALSO BE UTILIZED IN STATIN-INTOLERANT PATIENTS. OFF-LABEL USES FOR BEMPEDOIC ACID ARE UNKNOWN. THIS ACTIVITY REVIEWS THE INDICATIONS, MECHANISM OF ACTION, METHODS OF ADMINISTRATION, SIGNIFICANT ADVERSE EFFECTS, CONTRAINDICATIONS, AND MONITORING OF BEMPEDOIC ACID. BY UTILIZING THIS INFORMATION, HEALTHCARE PROVIDERS CAN EFFECTIVELY GUIDE PATIENT THERAPY AND ADDRESS HYPERLIPIDEMIA AS PART OF THE INTERPROFESSIONAL TEAM.