MOHS MICROGRAPHIC SURGERY CHEMOPROPHYLAXIS OPTIONS FOR NICOTINAMIDE AND ORAL RETINOIDS

Course overview

NICOTINAMIDE AND ORAL RETINOIDS ARE MEDICATIONS USED IN NON-MELANOMA SKIN CANCER PROPHYLAXIS. NICOTINAMIDE AND RETINOIDS ARE DERIVATIVES OF VITAMIN B3 AND VITAMIN A, RESPECTIVELY. PATIENTS WITH A SUBSTANTIALLY INCREASED RISK OF NON-MELANOMA SKIN CANCERS INCLUDE RECIPIENTS OF SOLID-ORGAN TRANSPLANTS, THOSE WITH CERTAIN GENODERMATOSES, AND INDIVIDUALS WITH EXTENSIVE CHRONIC SUN DAMAGE. THIS ACTIVITY REVIEWS THE INDICATIONS, MECHANISMS OF ACTION, CONTRAINDICATIONS, AND ADVERSE EVENT PROFILES FOR NICOTINAMIDE AND ORAL RETINOIDS AS CHEMOPROPHYLACTIC AGENTS FOR NON-MELANOMA SKIN CANCER. THIS ACTIVITY ALSO HIGHLIGHTS THE ROLE OF THE INTERPROFESSIONAL TEAM WHEN CARING FOR THIS PATIENT POPULATION.