Sr-82/Rb-82 Generator: Design & Operation

Course overview

This course will cover the Sr-82/Rb-82 Generator including a technical description of this radionuclide generator. It will include a description of the emissive properties of the Sr-82 parent and the Rb-82 daughter and information regarding its penetrability in human tissue; will list contraindications as well as possible side effects and adverse reactions related to this drug. Included is a summary of Generator Quality Control procedures. In addition, it will cover Dose administration procedures, imaging procedures, drug pharmacology and internal radiation dosimetry associated with the administration of Rb-82. In addition, it will discuss the parent/daughter relationship of a generator in secular equilibrium; will identify the route of administration, the typical prescribed dose, and the clinical pharmacology of the Rb-82 daughter; will describe the process of elution of the generator as well as the method of assessing quality control of the generator and the eluate and will include a brief summary of internal radiation dosimetry of the Rb-82 daughter, typically used for myocardial perfusion imaging,