Differentiating Sciatica vs Vascular Pain in a Middle Aged Male

Course overview

Distinguishing between sciatica and vascular pain can be clinically challenging, especially when peripheral arterial disease (PAD) presents with symptoms that closely mimic radicular patterns. This case study guides clinicians through the key historical features, red flags, and physical examination findings that help differentiate neurogenic from vascular sources of leg pain. It highlights the importance of recognising PAD-specific clues, understanding how activity and posture influence symptom onset, and appreciating the potential consequences of misdiagnosis. Clinicians will refine their clinical reasoning for complex lower-limb presentations and gain greater confidence in identifying cases requiring urgent referral.