CURRARINO SYNDROME

Course overview

Currarino syndrome (CS), also called Currarino triad, is an autosomal dominant genetic condition caused by a mutation in the HLXB9 homeobox gene, and is characterized by three clinical signs: a malformed sacrum, a mass in the presacral space in the anterior sacrum, and anorectal malformation. Other malformations associated with CS include rectovaginal fistula, duplex ureters, neurogenic bladder, renal abnormalities, and malignant degeneration of presacral teratoma. This continuing education module is designed to give the reader/learner an increased understanding of Currarino syndrome, including the etiology, clinical presentation, and potential complications of the disease, and to aid in the treatment of patients with this diagnosis. Readers may explore any or all of the topics. One contact hour of continuing education credit is available for those who successfully complete the post-test and evaluation form.