Challenges and Breakthroughs in Myositis Autoantibody Detection

Course overview

Myositis antibody testing continues to grow both in the number of patients tested and the number of laboratories offering this testing. However, significant variability exists in the diagnostic performance of these assays. This lecture will provide an overview of methods used and highlight the current challenges as well as some promising recent developments. After this presentation, participants will be able to: 1) Describe the importance of autoantibody profiling and panels of autoantibodies in idiopathic inflammatory myopathies (IIMs) 2) Discuss the need for robust methodologies for detecting myositis-specific antibodies (MSA)