Patellofemoral Pain Syndrome: Evidence-Based Update

Course overview

Patellofemoral pain syndrome remains one of the most prevalent and challenging musculoskeletal conditions encountered by rehabilitation professionals. Despite decades of research, clinicians continue to grapple with questions regarding optimal assessment strategies, treatment selection, and prognosis prediction. This continuing education course synthesizes the most current evidence from 2022 through 2025, providing rehabilitation professionals with practical, evidence-based strategies for managing this complex condition across diverse patient populations. The course is structured around seven integrated modules that progress from foundational epidemiological and pathophysiological concepts through clinical evaluation, biomechanical assessment, conservative management strategies, population-specific considerations, and outcome measurement. Each module builds upon previous content while maintaining clinical applicability as a standalone resource. The final module presents case studies that integrate concepts across all domains, reinforcing clinical decision-making skills. Recent advances in our understanding of patellofemoral pain have shifted the paradigm from a purely biomechanical model toward a biopsychosocial framework that acknowledges the interplay of structural, functional, and psychological factors. This course reflects that evolution, incorporating evidence on psychosocial contributors, digital therapeutics, and individualized treatment approaches. Special attention is given to sex-specific and sport-specific considerations, recognizing that patellofemoral pain manifests differently across populations and requires tailored management strategies. Upon completion of this course, participants will be equipped to apply current evidence in clinical practice, critically evaluate emerging research, and deliver patient-centered care that addresses the multifactorial nature of patellofemoral pain. The content aligns with best practice guidelines and consensus statements while highlighting areas of ongoing investigation and clinical uncertainty.