Functional Medicine and Nutrition Virtual Classroom 314 - Nutritional Genomics Foundations

Course overview

Describe how generative medicine and Hood's P4 framework apply systems biology to support proactive, personalized wellness care. Explain how SNPs, RS numbers, and odds ratios indicate genetic risk rather than diagnose disease. Describe how epigenetic methylation modulates gene expression and how TPH2 can be supported to enhance serotonin synthesis. Apply knowledge of MTHFR, tyrosine hydroxylase, and DDC to safely guide catecholamine precursor supplementation. Differentiate the roles of DBH, COMT, and MAOA in catecholamine breakdown and identify targeted nutrient interventions. Identify key aldehyde detoxification genes and agonists that support VMA and HVA metabolism. Explain the kynurenine pathway's production of quinolinic acid and NAD and the cofactors influencing its balance. Analyze patient cases by integrating SNP data, labs, and symptoms to tailor supplements for anxiety and depression.