Functional Medicine and Nutrition Virtual Classroom 305 - Functional Endocrinology

Course overview

Describe the hypothalamic-pituitary-thyroid feedback loop and identify cofactors required for peripheral T4-to-T3 conversion. Differentiate hyperthyroid and hypothyroid lab patterns and explain how iodine status and insulin resistance markers guide nutrient support. Analyze DHEA and cortisol physiology and interpret VMA and HVA organic acid markers to direct catecholamine-related nutrient interventions. Evaluate adrenal stress index patterns of cortisol and DHEA and recognize salivary markers reflecting chronic stress and gut barrier function. Describe estrogen biosynthesis from cholesterol and explain phase 1 hydroxylation and phase 2 conjugation pathways of estrogen metabolism. Apply the 2-hydroxy to 16-alpha-hydroxyestrone ratio in clinical decisions and recommend DIM dosing to improve estrogen metabolism. Evaluate testosterone status using total, free, and SHBG measurements and compare serum, saliva, and urine hormone testing methods. Interpret sample hormone panel case reports and apply the DPD urine test to monitor bone resorption interventions.