Loxapine
Tracking # 20-634789
Course overview
Loxapine is an antipsychotic that is used for the treatment of patients who have schizophrenia. It is known as a typical antipsychotic with high-potency effect, typically used in lower doses and titrated to effect. Loxapine has low activity at histaminic and muscarinic receptors so anticholinergic effects and sedation are less likely to occur, as compared to antipsychotics with low-potency effect. Loxapine use has been revisited in the literature most recently in terms of its usefulness for acute agitation and aggression for both child/adolescents and adults. More research however is needed on the potential benefits and risks of loxapine use in chronically mentally ill individuals or those with an acute, severe state of agitation and aggression, which may constitute a psychiatric emergency. No Test Required!
Subject areas
This course counts toward the state boards and subject areas below.
Arkansas State Board of Nursing
Certified Nurse Midwife
Certified Nurse Practitioner
Certified Registered Nurse Anesthetist
Clinical Nurse Specialist
Licensed Practical Nurse
Licensed Psychiatric Technician Nurse
Registered Nurse
Registered Nurse Practitioner
District of Columbia Board of Nursing
Certified Nurse Midwife
Clinical Nurse Specialist
Licensed Practical Nurse
Nurse Practitioner
Registered Nurse
Registered Nurse Anesthetist
Florida Board of Nursing
Advanced Practice Registered Nurse
Clinical Nurse Specialist
Licensed Practical Nurse
Registered Nurse
Georgia Board of Nursing
Licensed Practical Nurse
Registered Professional Nurse
New Mexico Board of Nursing
Certified Nurse Practitioner
Certified Registered Nurse Anesthetist
Clinical Nurse Specialist
Licensed Practical Nurse
Registered Nurse
South Carolina Board of Nursing
Advanced Practice Registered Nurse
Licensed Practical Nurse
Registered Nurse
West Virginia Board of Registered Nurses
Advanced Practice Registered Nurse
Registered Nurse
Disclosure statements
Policy Statement
This activity has been planned and implemented in accordance with the policies of NurseCe4Less.com and the continuing nursing education requirements of the American Nurses Credentialing Center's Commission on Accreditation for registered nurses.
Continuing Education Credit Designation
This educational activity is credited for 2.5 hours at completion of the activity. Pharmacology content is 2.5 hours.
Statement of Learning Need
Health clinicians need to know the indications, uses, contraindications and potential side effects of loxapine. While typical antipsychotic drug overdose does not generally cause life-threatening toxicity, a large overdose of loxapine can cause significant cardiac symptoms, coma, and seizures, which clinicians should be aware of when prescribing it. Loxapine can be used for all age groups, most recently revisited in the literature as appropriate for severe aggression and behavioral dysregulation.
Course Purpose
To inform health clinicians of current published information relative to basic pharmacological profile of loxapine and clinical pearls on topics that elucidate on the current research and case studies pertaining to the benefits and risk of loxapine use.
Target Audience
Advanced Practice Registered Nurses, Registered Nurses, and other Interdisciplinary Health Team Members.
Disclosures
Dana Bartlett, RN, BSN, MSN, MA, CSPI, William Cook, PhD, Douglas Lawrence, MA, Kellie Wilson, PharmD, Susan DePasquale, MSN, FPMHNP-BC – all have no disclosures. There is no commercial support.