Duloxetine
Tracking # 20-635311
Course overview
Duloxetine is an antidepressant that acts as a serotonin and norepinephrine reuptake inhibitor. It has labeled uses for the treatment of chronic musculoskeletal pain, diabetic peripheral neuropathic pain, fibromyalgia, generalized anxiety disorder, and major depressive disorder. Renal function is important in patients taking duloxetine because it is primarily excreted by the kidneys. In addition, the prescribing information states that the use of duloxetine should be avoided if a patient has cirrhosis or chronic hepatic disease since duloxetine may cause liver damage or exacerbate pre-existing liver disease. Since duloxetine is an antidepressant, there may be an increase in the risk of suicidal behavior and ideation in children, adolescents, and young adults with certain psychiatric disorders. No Test Required!
Subject areas
This course counts toward the state boards and subject areas below.
Arkansas State Board of Nursing
Certified Nurse Midwife
Certified Nurse Practitioner
Certified Registered Nurse Anesthetist
Clinical Nurse Specialist
Licensed Practical Nurse
Licensed Psychiatric Technician Nurse
Registered Nurse
Registered Nurse Practitioner
District of Columbia Board of Nursing
Licensed Practical Nurse
Registered Nurse
Florida Board of Nursing
Advanced Practice Registered Nurse
Clinical Nurse Specialist
Licensed Practical Nurse
Registered Nurse
Georgia Board of Nursing
Licensed Practical Nurse
Registered Professional Nurse
New Mexico Board of Nursing
Certified Nurse Practitioner
Certified Registered Nurse Anesthetist
Clinical Nurse Specialist
Licensed Practical Nurse
Registered Nurse
South Carolina Board of Nursing
Advanced Practice Registered Nurse
Licensed Practical Nurse
Registered Nurse
West Virginia Board of Registered Nurses
Advanced Practice Registered Nurse
Registered Nurse
Disclosure statements
Policy Statement
This activity has been planned and implemented in accordance with the policies of NurseCe4Less.com and the continuing nursing education requirements of the American Nurses Credentialing Center's Commission on Accreditation for registered nurses.
Continuing Education Credit Designation
This educational activity is credited for 2.5 hours at completion of the activity. Pharmacology content is 2.5 hours.
Statement of Learning Need
Health clinicians need to know the labelled and off-label uses, of duloxetine; as well as its contraindications and potential side effects. Renal function and monitoring for hyponatremia in patients prescribed duloxetine is an important consideration in addition to the drug’s effect on the liver. Its also important that clinicians are aware of the risk of suicidal behavior and ideation in all age groups, but more specifically children and adolescents.
Course Purpose
To inform health clinicians of current published information relative to basic pharmacological profile of duloxetine and clinical pearls on topics that help to elucidate the current research and case studies on the benefits and risks of duloxetine use.
Target Audience
Advanced Practice Registered Nurses, Registered Nurses, and other Interdisciplinary Health Team Members.
Disclosures
Dana Bartlett, RN, BSN, MSN, MA, CSPI, William Cook, PhD, Douglas Lawrence, MA, Kellie Wilson, PharmD, Susan DePasquale, MSN, FPMHNP-BC – all have no disclosures. There is no commercial support.