ASCP Scientific Updates 2018 Quarter 3 and 4 Package for Laboratory Professionals

Course overview

ASCP Scientific Updates are a quarterly series of 30-minute on-demand webcasts containing up-to-the-minute information on various therapeutic agents, disease states, and thresholds that impact immuno-oncology diagnostics in solid tumors and hematologic malignancies. Quarter 3: ASCP Scientific Updates: Tumor Mutational Burden This webcast will provide participants with a basic understanding of tumor mutational burden. You’ll learn what TMB is, TMB across different tumor types, and the types of mutational signatures that can be associated with high TMB. You will also learn the evidence for TMB as a biomarker in immuno-oncology, as well as the methods for TMB determination. Learning Objectives: As a result of participating in this course, learners will be able to: • Describe what tumor mutational burden is • Discuss the evidence for TMB as a biomarker in immuno-oncology • Describe the methods for TMB determination Faculty: Lauren Ritterhouse, MD, PhD Co-Director, Molecular Diagnostics and Clinical Genomics Laboratories Division of Genomic and Molecular Pathology The University of Chicago Quarter 4: Immuno-Oncology Scientific Updates: Liquid Biopsies: Current Limitations and Potential Applications This webcast provides an overview of the current limitations and potential applications of liquid biopsies in immuno-oncology. After a brief overview of current and emerging immuno-oncology biomarkers, you'll learn what liquid biopsies are and how they work. You will also learn which biomarkers are more applicable to liquid biopsy analysis as we discuss emerging applications of liquid biopsies in immuno-oncology. Learning Objectives: As a result of participating in this course, learners will be able to: • Describe current and emerging immuno-oncology biomarkers • Discuss liquid biopsies and how they work • Explain emerging applications of liquid biopsy in the field of immuno-oncology Faculty: Alexander J. Lazar, MD, PhD Professor, Department of Pathology, Division of Pathology/Lab Medicine Director, Selective (Soft Tissue) Pathology Fellowship Training Program, Department of Pathology Director, Sarcoma and Melanoma Clinical Genomics Program The University of Texas MD Anderson Cancer Center The American Society for Clinical Pathology is accredited by the Accreditation Council for Continuing Medical Education (ACCME) to provide continuing medical education for physicians. Credit Designation Statement The ASCP designates this enduring material for a maximum of 1.0 AMA PRA Category 1 Credit(s)™. Physicians should claim only credit commensurate with the extent of their participation in the activity. ASCP designates these enduring materials for a maximum of 1.0 CMLE credit. These activities meet CMP and state re-licensure requirements for laboratory personnel. For questions regarding CMLE credit, please contact ASCP Customer Service at 1-800-267-2727, during normal business hours: Monday through Friday, 8 a.m. to 6 p.m. Eastern Time Method of Participation To complete the activity and receive credit, the participant must complete the online course. CME certificates will be provided on-line. Funded by an independent educational grant from AstraZeneca.