Prazosin
Tracking # 20-646653
Course overview
Prochlorperazine is a phenothiazine with antiemetic effect and psychoactive properties. It has been widely used for many years in the prevention and relief of nausea, vomiting, vestibular and psychiatric disorders. The drug has well-known affinity for dopamine receptors, and muscarinic-cholinergic, histamine H1 and a-adrenoceptors. Prochlorperazine has been described as having slow absorption and a low bioavailability following oral dosing. Some researchers have evaluated the pharmacokinetics and pharmacodynamics of prochlorperazine after intravenous and oral dosing to determine the difference between the two dosing regimens. Adverse reactions to prochlorperazine generally occur with chronic dosing, such as Parkinsonism. Few published studies exist that compare prochlorperazine with other common antiemetic drugs in the treatment of specific disorders. Clinicians are recommended to choose a drug based upon the clinical scenario and patient preference related to drug administration and safety. No Test Required!
Subject areas
This course counts toward the state boards and subject areas below.
Arkansas State Board of Nursing
Certified Nurse Midwife
Certified Nurse Practitioner
Certified Registered Nurse Anesthetist
Clinical Nurse Specialist
Licensed Practical Nurse
Licensed Psychiatric Technician Nurse
Registered Nurse
Registered Nurse Practitioner
District of Columbia Board of Nursing
Certified Nurse Midwife
Clinical Nurse Specialist
Licensed Practical Nurse
Nurse Practitioner
Registered Nurse
Registered Nurse Anesthetist
Florida Board of Nursing
Advanced Practice Registered Nurse
Licensed Practical Nurse
Registered Nurse
Georgia Board of Nursing
Licensed Practical Nurse
Registered Professional Nurse
New Mexico Board of Nursing
Certified Nurse Practitioner
Certified Registered Nurse Anesthetist
Clinical Nurse Specialist
Licensed Practical Nurse
Registered Nurse
South Carolina Board of Nursing
Advanced Practice Registered Nurse
Licensed Practical Nurse
Registered Nurse
West Virginia Board of Registered Nurses
Advanced Practice Registered Nurse
Registered Nurse
Disclosure statements
Policy Statement
This activity has been planned and implemented in accordance with the policies of NurseCe4Less.com and the continuing nursing education requirements of the American Nurses Credentialing Center's Commission on Accreditation for registered nurses.
Continuing Education Credit Designation
This educational activity is credited for 2.5 hours at completion of the activity. Pharmacology content is 2.5 hours.
Statement of Learning Need
Clinicians need to know the indications, dosing and dosing adjustments, contraindications and potential side effects of prazosin. Prazosin is well-known for its benefit as an antihypertensive and to reduce symptoms related to post-traumatic stress disorder. However, clinicians should be aware that some experts have suggested that the trends in prazosin dosing for patients diagnosed with comorbid anxiety/panic in the setting of trauma is generally not high enough to achieve best outcomes.
Course Purpose
To inform health clinicians of current published information relative to the basic pharmacological profile and clinical pearls on prazosin.
Target Audience
Advanced Practice Registered Nurses, Registered Nurses, and other Interdisciplinary Health Team Members.
Disclosures
Kellie Wilson, PharmD, William Cook, PhD, Douglas Lawrence, MA, Susan DePasquale, MSN, FPMHNP-BC – All have no disclosures. There is no commercial support for this course.