Perphenazine
Tracking # 20-651361
Course overview
Perphenazine is a typical antipsychotic and a centrally acting dopamine D2 receptor antagonist with a labeled use to treat schizophrenia. It is also used to help allay symptoms of nausea and vomiting. Off-label, perphenazine is used to control agitation or psychosis caused by dementia, however clinicians are warned of the increased risk of death when using typical antipsychotics in elderly individuals. Use of perphenazine as with all first generation antipsychotics has been less preferred compared to second generation atypical antipsychotics that are associated with improved drug safety and tolerability. However, clinicians should also consider the longitudinal data associated with a clinical and therapeutic course of care in individual patients. Alongside a concern for drug safety and tolerance, antipsychotic drug treatment should also be tailored to individual patient symptoms and outcomes. No Test Required!
Subject areas
This course counts toward the state boards and subject areas below.
Arkansas State Board of Nursing
Certified Nurse Midwife
Certified Nurse Practitioner
Certified Registered Nurse Anesthetist
Clinical Nurse Specialist
Licensed Practical Nurse
Licensed Psychiatric Technician Nurse
Registered Nurse
Registered Nurse Practitioner
District of Columbia Board of Nursing
Certified Nurse Midwife
Clinical Nurse Specialist
Licensed Practical Nurse
Nurse Practitioner
Registered Nurse
Registered Nurse Anesthetist
Florida Board of Nursing
Advanced Practice Registered Nurse
Licensed Practical Nurse
Registered Nurse
Georgia Board of Nursing
Licensed Practical Nurse
Registered Professional Nurse
New Mexico Board of Nursing
Certified Nurse Practitioner
Certified Registered Nurse Anesthetist
Clinical Nurse Specialist
Licensed Practical Nurse
Registered Nurse
South Carolina Board of Nursing
Advanced Practice Registered Nurse
Licensed Practical Nurse
Registered Nurse
West Virginia Board of Registered Nurses
Advanced Practice Registered Nurse
Registered Nurse
Disclosure statements
Policy Statement
This activity has been planned and implemented in accordance with the policies of NurseCe4Less.com and the continuing nursing education requirements of the American Nurses Credentialing Center's Commission on Accreditation for registered nurses.
Continuing Education Credit Designation
This educational activity is credited for 2.5 hours at completion of the activity. Pharmacology content is 2.5 hours.
Statement of Learning Need
Health clinicians need to know the indications, uses, contraindications and potential side effects of perphenazine to provide safe and appropriate patient care. Warnings for perphenazine use should be shared with patients and families, such as use related to care of elderly patients with dementia and those with cognitive disabilities or other comorbid conditions. Also, clinicians should always bear in mind short- and long-term use of perphenazine when prescribing it as monotherapy on in conjunction with other medication.
Course Purpose
To inform health clinicians of current published information relative to basic pharmacological profile of perphenazine and clinical pearls to help elucidate the current research and case studies relative to the benefits and risks of perphenazine drug use.
Target Audience
Advanced Practice Registered Nurses, Registered Nurses, and other Interdisciplinary Health Team Members.
Disclosures
Dana Bartlett, RN, BSN, MSN, MA, CSPI, William Cook, PhD, Douglas Lawrence, MA, Susan DePasquale, MSN, FPMHNP-BC – all have no disclosures. There is no commercial support for this course.