Evaluation of Iron Stores by Zinc Protoporphyrin Analysis in Blood Donors

Course overview

Intended audience: clinical laboratory scientists, pathologists Keywords: blood bank, transfusion medicine, chemistry, hematology, ferritin, iron stores Educational objectives: • Understand why Zinc protoporphyrin (ZPP) testing has been studied as a substitute for ferritin (fer) testing of blood donors in determining iron stores. • To determine whether ZPP testing could be performed using specimens collected via the capillary (cap) finger-stick (FS) method, similar to predonation hemoglobin (HB) testing • Evaluate the correlation among FS HB, venous (ven) ZZP, FS ZPP, and ven ferritin (fer) levels as predictors of iron depletion.