Pimozide
Tracking # 20-697186
Course overview
Pimozide is a first generation antipsychotic drug that selectively blocks dopamine receptor D2 and is used to treat psychiatric mood disorders, schizophrenia, and other psychotic disorders. It works by reducing dopamine activity, hence decreasing excessive energy and excitation. Pimozide is FDA-approved for the treatment of Tourette syndrome, and may be used to augment selective serotonin reuptake inhibitor response in treatment-resistant refractory obsessive-compulsive disorder and obsessive-compulsive-related disorders. The drug has been reported to be effective in the treatment of behavioral symptoms in patients diagnosed with autism spectrum disorder. On the other hand, the benefit of pimozide as an adjunctive agent with certain antipsychotic drugs such as clozaril has been questioned. Researchers have revisited the use of pimozide in clinical practice given its relatively low side effect profile. Pimozide has been investigated most recently as a possible mediator of cancer suppression and anti-cancer agent. No Test Required!
Subject areas
This course counts toward the state boards and subject areas below.
Arkansas State Board of Nursing
Certified Nurse Midwife
Certified Nurse Practitioner
Certified Registered Nurse Anesthetist
Clinical Nurse Specialist
Licensed Practical Nurse
Licensed Psychiatric Technician Nurse
Registered Nurse
Registered Nurse Practitioner
District of Columbia Board of Nursing
Certified Nurse Midwife
Clinical Nurse Specialist
Licensed Practical Nurse
Nurse Practitioner
Registered Nurse
Registered Nurse Anesthetist
Florida Board of Nursing
Advanced Practice Registered Nurse
Licensed Practical Nurse
Registered Nurse
Georgia Board of Nursing
Licensed Practical Nurse
Registered Professional Nurse
New Mexico Board of Nursing
Certified Nurse Practitioner
Certified Registered Nurse Anesthetist
Clinical Nurse Specialist
Licensed Practical Nurse
Registered Nurse
South Carolina Board of Nursing
Advanced Practice Registered Nurse
Licensed Practical Nurse
Registered Nurse
West Virginia Board of Registered Nurses
Advanced Practice Registered Nurse
Registered Nurse
Disclosure statements
Policy Statement
This activity has been planned and implemented in accordance with the policies of NurseCe4Less.com and follows the requirements of the American Nurses Credentialing Center's Commission on Accreditation. It is the policy of NurseCe4Less.com to ensure objectivity, transparency, and best practice for online continuing education.
Continuing Education Credit Designation
This educational activity is credited for 2.5 hours at completion of the activity. Pharmacology content is 2.5 hours.
Statement of Learning Need
Clinicians need to know the indications, dosing and dosing adjustments, contraindications and potential side effects of pimozide. Specifically, pimozide may be effective in the treatment of Tourette syndrome, obsessive compulsive disorder and autism spectrum disorder. The benefit of pimozide as an adjunct to other psychotropic medications needs to be carefully reviewed within the current literature, and the benefits and risks weighed.
Course Purpose
To inform health clinicians of current published information relative to basic pharmacological profile of pimozide and clinical pearls on topics that were covered in the basic pharmacological profile.
Target Audience
Advanced Practice Registered Nurses, Registered Nurses, and other Interdisciplinary Health Team Members.
Disclosures
Dana Bartlett, RN, BSN, MSN, MA, CSPI, William Cook, PhD, Douglas Lawrence, MA, Susan DePasquale, MSN, FPMHNP-BC – all have no disclosures. There is no commercial support for this course.