Prochlorperazine
Tracking # 20-699728
Course overview
Prochlorperazine is a phenothiazine with antiemetic effect and psychoactive properties. It has been widely used for many years in the prevention and relief of nausea, vomiting, vestibular and psychiatric disorders. The drug has well-known affinity for dopamine receptors, and muscarinic-cholinergic, histamine H1 and a-adrenoceptors. Prochlorperazine has been described as having slow absorption and a low bioavailability following oral dosing. Some researchers have evaluated the pharmacokinetics and pharmacodynamics of prochlorperazine after intravenous and oral dosing to determine the difference between the two dosing regimens. Adverse reactions to prochlorperazine generally occur with chronic dosing, such as Parkinsonism. Few published studies exist that compare prochlorperazine with other common antiemetic drugs in the treatment of specific disorders. Clinicians are recommended to choose a drug based upon the clinical scenario and patient preference related to drug administration and safety. No Test Required!
Subject areas
This course counts toward the state boards and subject areas below.
Arkansas State Board of Nursing
Certified Nurse Midwife
Certified Nurse Practitioner
Certified Registered Nurse Anesthetist
Clinical Nurse Specialist
Licensed Practical Nurse
Licensed Psychiatric Technician Nurse
Registered Nurse
Registered Nurse Practitioner
District of Columbia Board of Nursing
Certified Nurse Midwife
Clinical Nurse Specialist
Licensed Practical Nurse
Nurse Practitioner
Registered Nurse
Registered Nurse Anesthetist
Florida Board of Nursing
Advanced Practice Registered Nurse
Licensed Practical Nurse
Registered Nurse
Georgia Board of Nursing
Licensed Practical Nurse
Registered Professional Nurse
New Mexico Board of Nursing
Certified Nurse Practitioner
Certified Registered Nurse Anesthetist
Clinical Nurse Specialist
Licensed Practical Nurse
Registered Nurse
South Carolina Board of Nursing
Advanced Practice Registered Nurse
Licensed Practical Nurse
Registered Nurse
West Virginia Board of Registered Nurses
Advanced Practice Registered Nurse
Registered Nurse
Disclosure statements
Policy Statement
This activity has been planned and implemented in accordance with the policies of NurseCe4Less.com and follows the requirements of the American Nurses Credentialing Center's Commission on Accreditation. It is the policy of NurseCe4Less.com to ensure objectivity, transparency, and best practice for online continuing education.
Continuing Education Credit Designation
This educational activity is credited for 2.5 hours at completion of the activity. Pharmacology content is 2.5 hours.
Statement of Learning Need
Clinicians need to know the indications, dosing and dosing adjustments, contraindications and potential side effects of prochlorperazine. As the most commonly used antiemetic in the phenothiazine class, prochlorperazine helps to reduce nausea that occurs with varied acute and chronic disorders. The drug can also be effective for patients suffering from acute anxiety and has a relatively low side effect profile.
Course Purpose
To inform health clinicians of current published information relative to basic pharmacological profile of prochlorperazine and clinical pearls on topics that were covered in the basic pharmacological profile.
Target Audience
Advanced Practice Registered Nurses, Registered Nurses, and other Interdisciplinary Health Team Members.
Disclosures
Dana Bartlett, RN, BSN, MSN, MA, CSPI, William Cook, PhD, Douglas Lawrence, MA, Susan DePasquale, MSN, FPMHNP-BC – all have no disclosures. There is no commercial support for this course.