Is Her Time Up? Understanding the Oocyte and the Factors that Mediate Reproductive Competence - POI and Infertility

Course overview

The oocyte is most influenced by a womans maternal grandmothers health and wellbeing than any other variable in her lifetime known as the trigenerational effect. In a clinical context when we are presented with a woman diagnosed with oocyte aging or premature ovarian insufficiency POI we are given a clinical conundrum that challenges our belief in current literature, ethical framework of practice and an awareness that some patients recover from oopause to resume cycling normally. How is this so and how can we optimise this for all women? There are key strategies we can incorporate that implement an understanding of oocyte biology and mitochondrial efficiency that can swing a womans fertility back into optimal cycling and oocyte health. Fertility care is inundated with women who face these diagnostic limitations and yearn for offspring from their own gametes. By understanding the requirements, considering new research and clinical expertise we can improve these statistics significantly and support women in achieving this goal.