The Complexity, Interplay and Sophistication of the Drivers of Endometriosis

Course overview

Endometriosis is a complicated chronic inflammatory condition. When patients are successful at conceiving, some are able to improve their endometriosis whilst others find it worsens and can develop into adenomyosis. Both conditions require a few key etiological considerations for treatment that reflect the sophistication and complexity of the conditions. Endometriosis and adenomyosis are both multifactorial and comprehensive by nature and are often simplified by clinicians which produce poor outcomes and reduced treatment success. The interplay between many aspects including the immune system, infective triggers, peritoneal fluid and the endocannabinoid system can have profound impact to the microbiome, methylation, epigenetics, inflammatory processes and endocrinological variables important in the progression and escalation of these conditions.