INSULIN RESISTANCE

Course overview

INSULIN RESISTANCE IS IDENTIFIED AS AN IMPAIRED BIOLOGIC RESPONSE TO INSULIN STIMULATION OF TARGET TISSUES, PRIMARILY THE LIVER, MUSCLE, AND ADIPOSE TISSUE. INSULIN RESISTANCE IMPAIRS GLUCOSE DISPOSAL, RESULTING IN A COMPENSATORY INCREASE IN BETA-CELL INSULIN PRODUCTION AND HYPERINSULINEMIA. THE METABOLIC CONSEQUENCES OF INSULIN RESISTANCE CAN RESULT IN HYPERGLYCEMIA, HYPERTENSION, DYSLIPIDEMIA, VISCERAL ADIPOSITY, HYPERURICEMIA, ELEVATED INFLAMMATORY MARKERS, ENDOTHELIAL DYSFUNCTION, AND A PROTHROMBIC STATE. THIS ACTIVITY REVIEWS THE CAUSE AND PRESENTATION OF INSULIN RESISTANCE AND HIGHLIGHTS THE ROLE OF THE INTERPROFESSIONAL TEAM IN ITS MANAGEMENT.