PARANEOPLASTIC LIMBIC ENCEPHALITIS

Course overview

PARANEOPLASTIC LIMBIC ENCEPHALITIS IS THOUGHT TO BE CAUSED BY AN ONCONEURAL ANTIBODY TO CANCER THAT CROSS-REACTS WITH SELF-ANTIGEN IN THE NEURONS AND MUSCLES. IT IS IS A RARE PARANEOPLASTIC SYNDROME THAT AFFECTS THE MEDIAL TEMPORAL LOBE AND MAY PRESENT WITH COGNITIVE DYSFUNCTION, CHANGE IN PERSONALITY, SEIZURE, IRRITABILITY, HALLUCINATIONS, DISORIENTATION, LIMBIC PARESIS, AND/ OR DISRUPTION OF CONSCIOUSNESS AND SHORT-TERM MEMORY LOSS. THIS ACTIVITY REVIEWS THE EVALUATION AND TREATMENT OF PARANEOPLASTIC LIMBIC ENCEPHALITIS AND HIGHLIGHTS THE ROLE OF THE INTERPROFESSIONAL TEAM IN THE DIAGNOSIS AND MANAGEMENT OF PATIENTS WITH THIS CONDITION.