OSLER-WEBER-RENDU DISEASE

Course overview

HEREDITARY HEMORRHAGIC TELANGIECTASIA (HHT) IS ALSO KNOWN AS OSLER–WEBER–RENDU DISEASE. IT IS AN AUTOSOMAL DOMINANT DISORDER CHARACTERIZED BY MULTIPLE MUCOCUTANEOUS TELANGIECTASIAS. THESE TELANGIECTASIAS REPRESENT SMALL ARTERIO-VENOUS MALFORMATIONS THAT FREQUENTLY TEND TO BLEEDS CAUSING THE PATIENT A SIGNIFICANT AMOUNT OF DISTRESS IN THEIR DAILY LIVES. PATIENTS TYPICALLY PRESENT WITH NOSE BLEEDS, GASTROINTESTINAL (GI) BLEEDS, AND IRON DEFICIENCY ANEMIA. THIS ACTIVITY REVIEWS THE PATHOPHYSIOLOGY OF OSLER WEBER RENDU SYNDROME AND HIGHLIGHTS THE ROLE OF THE INTERPROFESSIONAL TEAM IN ITS MANAGEMENT.