HIV-ASSOCIATED LIPODYSTROPHY

Course overview

HIV-ASSOCIATED LIPODYSTROPHY IS A SYNDROME CHARACTERIZED BY BODY HABITUS CHANGES ASSOCIATED WITH THE DEVELOPMENT OF INSULIN RESISTANCE, HYPERLIPIDEMIA, AND ENDOTHELIAL DYSFUNCTION THAT OCCUR SECONDARY TO ANTIRETROVIRAL THERAPY. LIPODYSTROPHY IS DEFINED AS A REDISTRIBUTION OF ADIPOSE TISSUE, WHICH CAN MANIFEST AS LIPOHYPERTROPHY, OR ACCUMULATION OF ADIPOSE TISSUE IN CENTRAL AREAS, AND/OR LIPOATROPHY, OR LOSS OF PERIPHERAL ADIPOSE TISSUE THAT IS COMMONLY SEEN IN EXTREMITIES, MALAR, AND TEMPORAL REGIONS. SEVERAL TREATMENT OPTIONS HAVE BEEN IDENTIFIED TO HELP DECREASE THE MORBIDITY AND MORTALITY THAT PATIENTS MAY EXPERIENCE DUE TO THIS CONDITION. THIS ACTIVITY REVIEWS THE EVALUATION AND MANAGEMENT OF HIV-ASSOCIATED LIPODYSTROPHY AND HIGHLIGHTS THE ROLE OF THE INTERPROFESSIONAL TEAM IN THE CARE OF PATIENTS AFFECTED BY THIS CONDITION.