VALPROATE TOXICITY

Course overview

VALPROATE IS A COMMONLY PRESCRIBED ANTICONVULSANT USED IN THE TREATMENT OF SEIZURE AND BIPOLAR DISORDERS. VALPROATE HAS ALSO BEEN UTILIZED FOR THE TREATMENT OF MIGRAINE HEADACHES AND IN THE SETTING OF ACUTE MANIA. VALPROATE IS AN ANTIEPILEPTIC DRUG WITH A BROAD MECHANISM OF ACTION. THIS CME ACTIVITY REVIEWS THE ETIOLOGY, EPIDEMIOLOGY, MECHANISM OF ACTION, PATHOPHYSIOLOGY, TOXICOKINETIC, AND HISTOPATHOLOGY OF VALPROATE TOXICITY. THIS ACTIVITY WILL FOCUS ON PHYSICAL EXAMINATION, DIAGNOSIS, MANAGEMENT, AND PROGNOSIS OF VALPROATE TOXICITY IN CLINICAL SETTINGS. IT ALSO EMPHASIZES PATIENT EDUCATION AND INTERPROFESSIONAL TEAM-BASED APPROACH NECESSARY FOR PATIENT-CENTERED CARE.