VON WILLEBRAND FACTOR

Course overview

REPLACEMENT THERAPY WITH VON WILLEBRAND FACTOR (VWF) CAN BE USED IN THE MANAGEMENT AND TREATMENT OF VON WILLEBRAND DISEASE (VWD) ESPECIALLY IN PATIENTS WHO ARE REFRACTORY TO TREATMENT WITH DESMOPRESSIN. IT IS AVAILABLE AS PLASMA-DERIVED CONCENTRATES AND MORE RECENTLY IN A RECOMBINANT FORM. THIS ACTIVITY REVIEWS THE INDICATIONS, ACTIONS, AND CONTRAINDICATIONS FOR THE USE OF VWF AS A THERAPEUTIC AGENT IN THE MANAGEMENT OF VWD. THIS ACTIVITY WILL HIGHLIGHT THE MECHANISM OF ACTION, ADVERSE EVENT PROFILE, AND OTHER KEY FACTORS LIKE DOSING, MONITORING, AND RELEVANT INTERACTIONS PERTINENT FOR MEMBERS OF THE INTERPROFESSIONAL TEAM INVOLVED IN THE CARE OF PATIENTS WITH VWD.