NOREPINEPHRINE

Course overview

UNTREATED HYPOTENSION CAN BE A SIGNIFICANT CAUSE OF MORBIDITY AND MORTALITY. NOREPINEPHRINE IS A FIRST-LINE AGENT FOR HYPOTENSION THAT DOES NOT RESPOND TO FLUID THERAPY AND CAN BE A POWERFUL ADJUNCT IN THE MANAGEMENT OF A CRITICALLY-ILL PATIENT. MEMBERS OF THE INTERPROFESSIONAL TEAM MUST BE KNOWLEDGEABLE ABOUT THE PHARMACOKINETICS AND PHARMACODYNAMICS, AS WELL AS THE INDICATIONS AND CONTRAINDICATIONS OF NOREPINEPHRINE USE SO THAT IT CAN BE UTILIZED EFFECTIVELY TO MANAGE HYPOTENSION THAT DOES NOT RESPOND TO VOLUME RESUSCITATION ALONE. THIS ACTIVITY REVIEWS THE INDICATIONS, CONTRAINDICATIONS, AND MECHANISM OF ACTION FOR NOREPINEPHRINE AS A VALUABLE AGENT IN THE MANAGEMENT OF HYPOTENSION AND HIGHLIGHTS THE ROLE OF THE INTERPROFESSIONAL TEAM IN CARING FOR PATIENTS WHO MAY BENEFIT FROM NOREPINEPHRINE.