HEMATOPOIETIC STEM CELL TRANSPLANTATION

Course overview

BONE MARROW TRANSPLANT, ALSO KNOWN AS HEMATOPOIETIC STEM CELL TRANSPLANT (HPSCT) INVOLVES THE ADMINISTRATION OF HEALTHY HEMATOPOIETIC STEM CELLS TO PATIENTS WITH DYSFUNCTIONAL OR DEPLETED BONE MARROW. THIS HELPS TO AUGMENT BONE MARROW FUNCTION AND, DEPENDING ON THE DISEASE BEING TREATED, LEADS TO EITHER DESTRUCTION OF MALIGNANT TUMOR CELLS OR TO GENERATION OF FUNCTIONAL CELLS THAT CAN REPLACE THE DYSFUNCTIONAL ONES, AS IS THE CASE OF IMMUNE-DEFICIENCY SYNDROMES, HEMOGLOBINOPATHIES, AND OTHER DISEASES. THIS ACTIVITY REVIEWS THE INDICATIONS, CONTRAINDICATIONS, AND COMPLICATIONS ASSOCIATED WITH HEMATOPOIETIC STEM CELL TRANSPLANTS AND HIGHLIGHTS THE ROLE OF THE INTERPROFESSIONAL TEAM IN THE MANAGEMENT OF PATIENTS REQUIRING THIS TREATMENT.