CANDESARTAN

Course overview

CANDESARTAN IS AN ORAL ANGIOTENSIN II RECEPTOR BLOCKER. IT IS AVAILABLE AS A PRO-DRUG, CANDESARTAN CILEXETIL, WHICH UNDERGOES HYDROLYSIS IN THE GASTROINTESTINAL TRACT DURING ABSORPTION TO ITS ACTIVE FORM. THE FDA APPROVED CANDESARTAN FOR THE MANAGEMENT OF HYPERTENSION IN ADULTS. CANDESARTAN IS ALSO USED OFF-LABEL FOR THE TREATMENT OF CONDITIONS INCLUDING CEREBROVASCULAR ACCIDENT OR STROKE, DIABETIC NEPHROPATHY, LEFT VENTRICULAR HYPERTROPHY, AND MIGRAINES. THIS ACTIVITY REVIEWS THE MECHANISM OF ACTION, ADVERSE EVENT PROFILE, TOXICITY, DOSING, PHARMACODYNAMICS, AND MONITORING OF CANDESARTAN, PERTINENT FOR CLINICIANS AND OTHER MEMBERS OF THE INTERPROFESSIONAL TEAM SO THAT THIS DRUG CAN BE UTILIZED WHEN INDICATED.