BIOTIN DEFICIENCY

Course overview

BIOTIN IS A B-COMPLEX VITAMIN THAT SERVES AS AN ESSENTIAL COENZYME FOR FIVE CARBOXYLASES: PYRUVATE CARBOXYLASE, 3-METHYLCROTONYL-COA CARBOXYLASE, PROPIONYL-COA CARBOXYLASE, AND COENZYME FOR ACETYL-COA CARBOXYLASES 1 AND 2. BIOTIN DEFICIENCY AFFECTS THE ACTIVITY OF BIOTIN-DEPENDENT CARBOXYLASES. THESE CARBOXYLASES FACILITATE VARIOUS METABOLIC REACTIONS SUCH AS GLUCONEOGENESIS, FATTY ACID SYNTHESIS, AND AMINO ACID METABOLISM. THIS ACTIVITY REVIEWS THE EVALUATION OF BIOTIN DEFICIENCY AND HIGHLIGHTS THE HEALTHCARE TEAM'S ROLE IN EVALUATING AND TREATING PATIENTS WITH THIS CONDITION.