ANTIEMETIC NEUROKININ-1 RECEPTOR BLOCKERS

Course overview

NEUROKININ-1 (NK-1) RECEPTOR ANTAGONISTS ARE A NEW CLASS OF ANTIEMETIC DRUGS THAT POSSESS UNIQUE ANXIOLYTIC, ANTIDEPRESSANT, AND ANTIEMETIC PROPERTIES. THE DISCOVERY OF NEUROKININ-1 (NK-1) RECEPTOR BLOCKERS WAS A CRUCIAL POINT IN THE PREVENTION OF EMESIS ASSOCIATED WITH CANCER CHEMOTHERAPY. THIS ACTIVITY REVIEWS THE INDICATIONS, CONTRAINDICATIONS, ACTIVITY, ADVERSE EVENTS, AND OTHER KEY ELEMENTS OF ANTIEMETIC NEUROKININ-1 RECEPTOR BLOCKERS IN THE CLINICAL SETTING AS RELATES TO THE ESSENTIAL POINTS NEEDED BY MEMBERS OF AN INTERPROFESSIONAL TEAM MANAGING THE CARE OF PATIENTS WHO CAN BENEFIT THERAPEUTICALLY FROM THESE AGENTS.