AMINOGLYCOSIDES

Course overview

WHILE AMINOGLYCOSIDES ARE AN OLDER CLASS OF MEDICATION, THEY CONTINUE TO BE CLINICALLY VALUABLE. AMINOGLYCOSIDES HAVE A BROAD SPECTRUM OF ACTIVITY COVERING AEROBIC ORGANISMS, INCLUDING GRAM-NEGATIVE BACTERIA AND MYCOBACTERIA. THERE ARE SEVERAL DRUGS WITHIN THE AMINOGLYCOSIDE CLASS, INCLUDING GENTAMICIN, TOBRAMYCIN, AMIKACIN, NEOMYCIN, PLAZOMICIN, AND STREPTOMYCIN, AND FDA APPROVED INDICATIONS VARY BETWEEN THE FOR THESE INDIVIDUAL AMINOGLYCOSIDES. THIS ACTIVITY REVIEWS THE INDICATIONS, CONTRAINDICATIONS, MECHANISM OF ACTION, ADVERSE EVENT PROFILE, AND OTHER KEY FACTORS (E.G., OFF-LABEL USES, DOSING, PHARMACODYNAMICS, PHARMACOKINETICS, MONITORING, RELEVANT INTERACTIONS) PERTINENT TO MEMBERS OF THE INTERPROFESSIONAL TEAM WHO WISH TO PRESCRIBE AMINOGLYCOSIDES.