von Willebrand Disease: An Inherited Bleeding Disorder

Course overview

Von Willebrand disease (vWD) is the most common inherited genetic bleeding disorder, yet it is not well known or understood among the public or healthcare providers. Von Willebrand factor (vWF) is a protein that is essential for platelet aggregation and clotting. A low vWF can lead to heavy or prolonged bleeding. This most commonly appears as complaints of menorrhagia (i.e., heavy menstrual bleeding), prolonged bleeding after minor injuries, or gum bleeding. The clinician can advocate for proper diagnosis and treatment, as well as prevent adverse events by being aware of the presenting signs and types of the disorder, recognizing that many patients are asymptomatic, and understanding when a hematology consultation is warranted.