Can the Use of the More Esoteric Antibodies Aid in Optimizing the Diagnosis for the Patient? (OLC)

Course overview

Many Histology labs today also include Immunohistochemistry as an essential part of surgical pathology. However, the use of the more esoteric antibodies are often left to a larger lab for several reasons; some include validation time, tech experience and tech time setting up the new antibodies, cost. But is this optimal for the patient?? Utilizing more esoteric antibodies one can better diagnosis subtle differences between a disease process such as an inflammatory process, versus an autoimmune disease versus a carcinoma. Locating a source for the esoteric antibodies can be challenging. Which clone or polyclonal do I choose? Various other analytic considerations are titer, pretreatment, protocol, the chromogen. To. Prior to the test going Live, positive controls will be needed and the technologists performing the test will need to sign off on the test. Some of these antibodies are CXCR5, Carbonic anhydrase, NKX3.1, Olig 2, and IMP3. This workshop will consist of the technical aspects as well as the interpretive views and experience of the pathologist.