SUCRALFATE

Course overview

SUCRALFATE IS A MEDICATION USED TO TREAT DUODENAL ULCERS, EPITHELIAL WOUNDS, CHEMOTHERAPY-INDUCED MUCOSITIS, RADIATION PROCTITIS, ULCERS IN BEHCET DISEASE, AND BURN WOUNDS. SUCRALFATE EXHIBITS ITS ACTION BY FORMING A PROTECTIVE LAYER, INCREASING BICARBONATE PRODUCTION, EXHIBITING ANTI-PEPTIC EFFECTS, PROMOTING TISSUE GROWTH, REGENERATION, AND REPAIR. THE MOST COMMON SIDE EFFECT SEEN WITH THIS DRUG IS CONSTIPATION. SOME OF THE MORE SEVERE SIDE EFFECTS ARE HYPOPHOSPHATEMIA, ALUMINUM INTOXICATION SEEN IN END-STAGE DISEASE PATIENTS. THE MEDICATION HAS A RELATIVELY SAFE PROFILE AS THERE IS NEGLIGIBLE ABSORPTION FROM THE ENTERAL SYSTEM. THIS ACTIVITY OUTLINES THE INDICATIONS, MECHANISM OF ACTION, METHODS OF ADMINISTRATION, SIGNIFICANT ADVERSE EFFECTS, CONTRAINDICATIONS, TOXICITY, AND MONITORING, OF SUCRALFATE, SO PROVIDERS CAN DIRECT PATIENT THERAPY IN CONDITIONS WHERE IT HAS THERAPEUTIC BENEFIT AS PART OF THE INTERPROFESSIONAL TEAM.