AMPHOTERICIN B

Course overview

AMPHOTERICIN B DEOXYCHOLATE BELONGS TO THE POLYENE CLASS OF ANTIFUNGALS. IT IS ALSO KNOWN BY THE CONVENTIONAL NAME AMPHOTERICIN B AND HAS BEEN USED FOR THE TREATMENT OF INVASIVE FUNGAL INFECTIONS FOR MORE THAN 50 YEARS. NEWER LIPID FORMULATIONS THAT ARE LESS NEPHROTOXIC AS COMPARED WITH CONVENTIONAL AMPHOTERICIN B ARE AVAILABLE. THIS ACTIVITY REVIEWS THE INDICATIONS, CONTRAINDICATIONS, ACTIVITY, ADVERSE EVENTS, TOXICITY, AND OTHER KEY ELEMENTS OF ANTIFUNGAL USES OF AMPHOTERICIN B IN THE CLINICAL SETTING AS RELATES TO THE ESSENTIAL POINTS NEEDED BY MEMBERS OF AN INTERPROFESSIONAL TEAM MANAGING THE CARE OF PATIENTS WHO PRESENT WITH MYCOTIC INFECTIONS.