AGAMMAGLOBULINEMIA

Course overview

AGAMMAGLOBULINEMIA OR HYPOGAMMAGLOBULINEMIA IS A RARE INHERITED IMMUNODEFICIENCY DISORDER, CHARACTERIZED BY LOW OR ABSENT B CELLS WITH ABSENT IMMUNOGLOBULINS. X-LINKED AGAMMAGLOBULINEMIA BEING THE MOST COMMON TYPE. MAINLY PRESENTS AFTER 6 TO 9 MONTHS OF AGE WHEN MATERNAL ANTIBODIES WEAR OFF. THIS CAN LEAD TO LIFE-THREATENING RECURRENT SINOPULMONARY AND GASTROINTESTINAL INFECTIONS. TO AVOID THE HIGH MORBIDITY AND MORTALITY ASSOCIATED WITH THIS CONDITION, IT MUST BE PROMPTLY DIAGNOSED AND TREATED. THIS ACTIVITY REVIEWS THE EVALUATION AND TREATMENT OF AGAMMAGLOBULINEMIA AND HIGHLIGHTS THE ROLE OF THE INTERPROFESSIONAL TEAM IN EVALUATING AND TREATING PATIENTS WITH THIS CONDITION.