BACLOFEN

Course overview

BACLOFEN IS USED TO TREAT MUSCLE SPASTICITY; IT IS FDA-APPROVED FOR THE MANAGEMENT OF REVERSIBLE SPASTICITY, PARTICULARLY FOR THE RELIEF OF FLEXOR SPASMS, CLONUS, AND CONCOMITANT PAIN, COMMON SEQUELAE OF SPINAL CORD LESIONS, AND MULTIPLE SCLEROSIS. BACLOFEN ALSO HAS SEVERAL OFF-LABEL USES. THIS ACTIVITY OUTLINES THE INDICATIONS, MECHANISM OF ACTION, SAFE ADMINISTRATION, ADVERSE EFFECTS, CONTRAINDICATIONS, TOXICOLOGY, AND MONITORING OF THE BROAD ARRAY OF PHYSIOLOGICAL POSSIBILITIES WHEN USING BACLOFEN IN THE CLINICAL SETTING.