ALLERGY AND IMMUNOLOGY 202

Course overview

Hour 1 *List the cells where histamine is predominantly found. *Describe the role of the Mast Cell. *Explain histamine's function and recall what causes its release. *List the Histamine receptor types and where each is found. *Summarize or give examples of symptoms in over activation of histamine receptors. *Many of our patients are on OTC Antihistamine medications. List their effects, positive and negative. Hour 2 *Quote what OAS stands for. *Define OAS and describe what happens to those with this problem. *Recognize at what age(s) OAS occurs. *Memorize, recognize, and describe 1-5 OAS examples. *Educate your patient on how to deal with OAS. *Describe NFkB as a system. *Describe NFkB's role in canonical and non-canonical pathways. *Explain what IkBa is and its potential role in downregulating inflammation. Hour 3 *Discuss how specific herbs, nutrients, and Vitamin E work to manage histamine at both a macro and microscopic level. *Be able to describe allergic inflammation. *Discover how NSAIDs are being noted to reduce CNS diseases with inflammation and may help manage allergic disorder(s). *Identify what particular NSAID is naturally occurring and available to us and your patients to help them manage their allergic inflammation. *Calculate its clinical dose and avoid its lethal dose. *List various SPMs (Specialized Proresolving Mediators) *Describe how SPMs can control IgE production and play a potential role in the treatment of Alzheimer's Disease. *Relate histamine's role in IBS (Irritable Bowel), name and synthesize the type of 2 known GI receptors involved.