Drug-Induced Kidney and Liver Injury

Course overview

Drug-induced kidney and liver injury is a major problem throughout the world. Some of the most commonly prescribed drugs are involved in the pathogenesis of kidney and liver toxicity, including antibiotics, acetaminophen (Tylenol), non-steroidal anti-inflammatory drugs (NSAIDs) (e.g., ibuprofen [Advil]), and angiotensin-converting enzyme (ACE) inhibitors. These frequently prescribed medications can result in kidney and liver toxicities, and many are available over the counter. Therefore, it is imperative that healthcare providers are aware of which agents commonly cause kidney or liver injury, symptoms that may indicate toxicity, abnormalities in lab values that indicate kidney or liver injury, and potential preventive measures.