An Update on HPV Versus Non-HPV-Associated Endocervical Adenocarcinoma

Course overview

Recent studies have focused on more detailed characterizations of endocervical adenocarcinomas which are not HPV driven. Additionally, the 5th edition of the WHO Classification of Tumours-Female Genital Tumours has been recently released. Using clinical cases, this presentation aims to highlight recent updates in the morphologic diagnosis and workup of both HPV-associated and HPV-independent invasive endocervical adenocarcinomas. After this presentation, participants will be able to: 1) Describe updates from the 5th edition of the WHO Classification of Tumours-Female Genital Tumours (Uterine Cervix) 2) Recognize HPV-associated adenocarcinomas of the endocervix pattern-based assessment of invasive carcinoma (Silva classification) 3) Identify HPV-independent adenocarcinomas of the endocervix based on International Endocervical Adenocarcinoma Criteria and Classification (IECC) and proposed algorithmic workup