Lithium and Thyroid Complications

Course overview

Lithium is a psychotropic drug that is established as an effective treatment for mania and the maintenance of bipolar disorder. While lithium is an effective treatment, it is well known to have adverse effects across many organ systems. Endocrinopathies, including thyroid abnormalities, are among the most common complications found with lithium treatment. This review will cover the effects of lithium on the physiology of the thyroid gland and the more common thyroid abnormalities associated with lithium use. In addition, it will discuss lithium and its use in special population groups, such as children and the elderly, as well as monitoring and treatment guidelines for lithium-induced thyroid abnormalities.