Droperidol

Course overview

Droperidol is a butyrophenone class typical antipsychotic that has a labeled use in the United States for the reduction of nausea and vomiting that accompany diagnostic and surgical procedures. It is used for various off-label indications, such as to sedate acutely agitated or violent patients, to treat acute migraine, and as an adjunct for general anesthesia induction and maintenance. Pharmacists should be aware of the controversial nature of the usage restrictions of this drug, the history of the drugs disappearance and re-emergence from use in the United States, and the risks and benefits associated with its use.