ZILEUTON

Course overview

ZILEUTON IS A 5-LIPOXYGENASE INHIBITOR MAINLY USED FOR THE PROPHYLAXIS AND TREATMENT OF CHRONIC ASTHMA FOR PATIENTS AGED 12 AND OLDER. ZILEUTON IS USED ALONG WITH INHALED CORTICOSTEROIDS FOR TREATMENT. IT CAN ALSO BE USED IN PATIENTS WITH ASPIRIN-INDUCED ASTHMA. WHILE IT IS NOT INDICATED FOR PATIENTS WITH AN ACUTE ASTHMA ATTACK, RESEARCH HAS ALSO SHOWN ZILEUTON TO HELP TREAT PATIENTS WITH CHRONIC OBSTRUCTIVE PULMONARY DISEASE, UPPER AIRWAY INFLAMMATORY CONDITIONS, AND DERMATOLOGICAL CONDITIONS SUCH AS ACNE, PRURITIC IN SJOGREN-LARSSON SYNDROME, AND ATOPIC DERMATITIS. THIS ACTIVITY OUTLINES THE INDICATIONS, MECHANISM OF ACTION, METHODS OF ADMINISTRATION, SIGNIFICANT ADVERSE EFFECTS, CONTRAINDICATIONS, TOXICITY, AND MONITORING, OF ZILEUTON. IT ALSO HIGHLIGHTS THE ROLE OF INTERPROFESSIONAL TEAMS SO THAT PROVIDERS CAN DIRECT PATIENT THERAPY USING ZILEUTON IN ASTHMA RELIEF.