HEMOGLOBIN C DISEASE

Course overview

HEMOGLOBIN C IS A COMMON HEMOGLOBIN VARIANT THAT HAS A SINGLE AMINO ACID SUBSTITUTION (LYSINE SUBSTITUTED FOR THE GLUTAMATE) IN THE SIXTH POSITION OF THE BETA-GLOBIN CHAIN. THE PATIENTS WITH HEMOGLOBIN C TRAIT (HBAC) ARE PHENOTYPICALLY NORMAL, WHILE PATIENTS WITH HEMOGLOBIN C DISEASE (HBCC) MAY HAVE CHRONIC HEMOLYTIC ANEMIA. THIS ACTIVITY REVIEWS THE EVALUATION AND MANAGEMENT OF HEMOGLOBIN C DISEASE AND HIGHLIGHTS THE ROLE OF THE INTERPROFESSIONAL TEAM IN IMPROVING CARE FOR PATIENTS WITH THIS CONDITION.