APREPITANT

Course overview

APREPITANT IS A MEDICATION USED TO MANAGE AND TREAT CHEMOTHERAPY-INDUCED NAUSEA AND VOMITING (CINV) AND POSTOPERATIVE NAUSEA AND VOMITING (PONV). IT IS IN THE NEUROKININ-1 ANTAGONIST CLASS OF MEDICATIONS. THIS ACTIVITY OUTLINES AND REVIEWS THE INDICATIONS, ACTIONS, AND CONTRAINDICATIONS FOR APREPITANT AS A VALUABLE AGENT IN PREVENTING AND MANAGING CINV AND PONV. THIS ACTIVITY WILL ALSO HIGHLIGHT THE MECHANISM OF ACTION, ADVERSE EVENT PROFILE, AND OTHER KEY FACTORS (E.G., OFF-LABEL USES, DOSING, PHARMACODYNAMICS, PHARMACOKINETICS, MONITORING, RELEVANT INTERACTIONS) PERTINENT FOR MEMBERS OF THE HEALTHCARE TEAM IN THE MANAGEMENT OF PATIENTS EITHER RECEIVING HIGHLY EMETOGENIC CHEMOTHERAPY OR GENERAL ANESTHESIA.